International Journal of Cardiology
Volume 127, Issue 1 , Pages 27-32 , 23 June 2008

Longer-term bosentan therapy improves functional capacity in Eisenmenger syndrome: Results of the BREATHE-5 open-label extension study

  • Michael A. Gatzoulis

      Affiliations

    • Royal Brompton Hospital and the National Heart and Lung Institute, Imperial College, London, UK
    • Corresponding Author InformationCorresponding author. Royal Brompton Hospital and the National Heart and Lung Institute, Imperial College, Sydney Street, London, SW3 6NP, UK. Tel.: +44 207 351 8602; fax: +44 207 351 8367.
  • ,
  • Maurice Beghetti

      Affiliations

    • Hôpital des Enfants, Geneva, Switzerland
  • ,
  • Nazzareno Galiè

      Affiliations

    • Istituto di Cardiologia, Università di Bologna, Bologna, Italy
  • ,
  • John Granton

      Affiliations

    • Toronto General Hospital, Toronto, Canada
  • ,
  • Rolf M.F. Berger

      Affiliations

    • University Medical Center Groningen, University of Groningen, The Netherlands
  • ,
  • Andrea Lauer

      Affiliations

    • Actelion Pharmaceuticals Ltd., Allschwil, Switzerland
  • ,
  • Eleonora Chiossi

      Affiliations

    • Actelion Pharmaceuticals Ltd., Allschwil, Switzerland
  • ,
  • Michael Landzberg

      Affiliations

    • Children's Hospital, Boston, MA, USA
  • ,
  • on behalf of the BREATHE-5 Investigators

Received 26 February 2007 ,Accepted 26 April 2007.

References 

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PII: S0167-5273(07)01043-1

doi: 10.1016/j.ijcard.2007.04.078

International Journal of Cardiology
Volume 127, Issue 1 , Pages 27-32 , 23 June 2008