International Journal of Cardiology
Volume 125, Issue 2 , Pages 197-202 , 10 April 2008

Diastolic heart failure in the elderly: Underlying mechanisms and clinical relevance

  • Ken McDonald

      Affiliations

    • Corresponding Author InformationTel.: +353 1 2304629; fax: +353 1 2304639.

References 

  1. Kannel WB. Epidemiology and prevention of cardiac failure: Framingham Study insights. Eur Heart J. 1987;8:23–26[Suppl F]
  2. Young JB. The global epidemiology of heart failure. Med Clin North Am. 2004;88:115–143
  3. Pihl E, Jacobsson A, Fridlund B, Stromberg A, Martensson J. Depression and health related quality life in elderly patients suffering from heart failure and their spouses; a comparative study. Eur J Heart Fail. 2005;7:583–589
  4. Stewart S, MacIntyre K, MacLeod MM, Bailey AE, Capewell S, McMurray JJ. Trends in hospitalisation for heart failure in Scotland, 1990–1996. An epidemic that has reached its peak?. Eur Heart J. 2001;22:209–217
  5. Stewart S, Jenkins A, Buchan S, McGuire A, Capewell A, McMurray JJ. The current cost of heart failure to the National Health Service in the U.K. Eur J Heart Fail. 2002;4:361–371
  6. Linne AB, Liedholm H, Jendteg S, Israelsson B. Health care costs of heart failure: results from a randomised study of patient education. Eur J Heart Fail. 2000;2:291–297
  7. Metra M, Ponikowski P, Dickstein K, et al. on behalf of the Heart Failure Association of the European Society of Cardiology Advanced chronic heart failure; a position statement from the study group on advanced heart failure of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail. 2007;9:684–694
  8. Owan TE, Hodge DO, Herges RM, Jacobsen SJ, Roger VL, Redfield MM. Trends in prevalence and outcome of heart failure with preserved ejection fraction. N Engl J Med. 2006;355:251–259
  9. Bhatia RS, Tu JV, Lee DS, et al. Outcome of heart failure with preserved ejection fraction in a population-based study. N Eng J Med. 2006;355:260–269
  10. Bonow EO, Udelson JE. Left ventricular diastolic dysfunction as a cause of congestive heart failure. Ann Intern Med. 1992;92:2764–2784
  11. Grossman W. Diastolic dysfunction in congestive heart failure. N Engl J Med. 1991;325:1557–1564
  12. Brutsaert DI, Sys SU, Gilleert TC. Diastolic failure: pathophysiology and therapeutic implications. J Am Coll Cardiol. 1993;22:318–325
  13. Paulus WJ, Tschope C, Sanderson JE, et al. How to diagnose diastolic heart failure; a consensus statement on the diagnosis of heart failure with normal ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology. Eur Heart J. 2008;28:2539–2550
  14. Yu C-M, Zhang Q, Yip GWK, et al. Diastolic and systolic asynchrony in patients with diastolic heart failure. J Am Coll Cardiol. 2007;49:97–105
  15. Wang J, Kurelmeyer , Torre-Amione G, Nagueh SF. Systolic and diastolic dyssynchrony in patients with diastolic heart failure and the effect of medical therapy. J Am Coll Cardiol. 2007;49:88–96
  16. Wang M, Yip GWK, Wang A, et al. Tissue Doppler imaging provides incremental prognostic value in patients with hypertension and left ventricular hypertrophy. J Hypertens. 2005;23:183–191
  17. Baicu CF, Zile MR, Aurigemma GP, Gaasch WH. Left ventricular systolic performance, function and contractility in patients with diastolic heart failure. Circulation. 2005;111:2306–2312
  18. Lubien E, DeMaria A, Krishnaswamy P, et al. Utility of B-natriuretic peptide in detecting diastolic dysfunction: comparison with Doppler velocity recordings. Circulation. 2002;105:595–601
  19. Vasan RS, Benjamin EJ, Levy D. Prevalence, clinical features and prognosis of diastolic heart failure: an epidemiologic perspective. J Am Coll Cardiol. 1995;26:1565–1574
  20. McCullough PA, Khandelwal AK, McKinnon , et al. Outcomes and prognostic factors of systolic as compared with diastolic heart failure in urban America. Congest Heart Fail. 2005;11:6–11
  21. Abhayaratna WP, Marwick TH, Smith WT, Becker NG. Characteristics of left ventricular diastolic dysfunction in the community: an echocardiographic survey. Heart. 2006;92:1259–1264
  22. Dauterman KW, Massie BM, Gheorghiade M. Heart failure associated with preserved systolic function: a common and costly clinical entity. Am Heart J. 1998;135:310–319[Suppl]
  23. Mitchell JA, Ventura HO, Mehra MR. Early recognition and treatment of hypertensive heart disease. Curr Opin Cardiol. 2005;20:282–289
  24. Galderisi M. Diastolic dysfunction and diabetic cardiomyopathy. J Am Coll Cardiol. 2006;48:1548–1551
  25. Seiler C, Pohl T, Lipp E, Hutter D, Meier B. Regional left ventricular function during transient ischaemia: relation with coronary collateral flow. Heart. 2002;88:35–42
  26. Urheim S, Edvardsen T, Steine K, et al. Postsystoic shortening of ischaemic myocardium: a mechanism of abnormal ventricular filling. Am J Physiol Heart Circ Physiol. 2003;284:H2343–H2350
  27. Fleg JL. Alterations in cardiovascular structure and function with advancing age. Am J Cardiol. 1986;239:33C–44C
  28. Chinnaiyan KM, Alexander D, Maddens M, McCullough PA. Curriculum in cardiology: integrated diagnosis and management of diastolic heart failure. Am Heart J. 2007;153:189–200
  29. Kawaguchi M, Hay I, Fetics , et al. Combined ventricular and arterial stiffening in patients with heart failure and preserved ejection fraction: implications for systolic and diastolic limitations. Circulation. 2003;107:714–720
  30. Gradman AH, Alfayoumi F. From left ventricular hypertrophy to congestive heart failure: management of hypertensive heart disease. Prog Cardiovas Dis. 2006;48:326–341
  31. Galderisi M, Cical S, Caso P, et al. Coronary flow reserve and myocardial diastolic dysfunction in arterial hypertension. Am J Cardiol. 2002;90:860–864
  32. Diez J, Panizo A, Gil MJ, Monreal I, Hernandez M, Pardo MJ. Serum markers of collagen type I metabolism in spontaneously hypertensive rats: relation to myocardial fibrosis. Circulation. 1996;28:269–275
  33. Brilla CG, Matsubara L, Weber KT. Advanced hypertensive heart disease in spontaneously hypertensive rats; lisinopril-mediated regression of myocardial fibrosis. Hypertension. 1996;28:269–275
  34. Querejeta R, Lopez B, Gonzalez A, et al. Increased collagen type I synthesis in patients with heart failure of hypertensive origin: relation to myocardial fibrosis. Circulation. 2004;110:1263–1268
  35. Brilla CG, Funck RC, Rupp H. Lisinopril-mediated regression of myocardial fibrosis in patients with hypertensive heart disease. Circulation. 2000;102:1388–1393
  36. Martos R, Baugh J, Ledwidge M, et al. Diastolic heart failure. Evidence of increased myocardial collagen turnover linked to diastolic dysfunction. Circulation. 2007;115:888–895
  37. Dahlof B, Hansson L. Regression of left ventricular hypertrophy in previously untreated essential hypertension: different effects of enalapril and hydrochlorthiazide. J Hypertens. 1992;10:1513–1524
  38. Cuilla M, Paliotti R, Esposito A, et al. Different of antihypertensive therapies based on losarten or atenolol on ultrasound and biochemical markers of myocardial fibrosis. Circulation. 2004;110:552–557
  39. Grandi AM, Imperiale D, Santillo R, et al. Aldosterone antagonist improves diastolic function in essential hypertension. Hypertension. 2002;40:647–652
  40. Yusuf S, Pfeffer MA, Swedberg K, et al. Effects of candesarten in patients with chronic heart failure and preserved left ventricular ejection fraction: the CHARM-Preseved Trial. Lancet. 2003;362:777–781
  41. Persson H, Lonn E, Edner M, et al. Diastolic dysfunction in heart failure with preserved systolic function: need for objective evidence. J Am Coll Cardiol. 2007;49:687–694
  42. Cleland JG, Tendera M, Adamus J, et al. The perindopril in elderly people with chronic heart failure (PEP-CHF) study. Eur Heart J. 2006;27:2338–2345
  43. Zannad F, Alla F, Dousset B, Perez A, Pitt B. Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure; insights from the Randomised Aldactone Evaluation Study (RALES); RALES Investigators. Circulation. 2000;102:2700–2706

PII: S0167-5273(07)01617-8

doi: 10.1016/j.ijcard.2007.10.002

International Journal of Cardiology
Volume 125, Issue 2 , Pages 197-202 , 10 April 2008