International Journal of Cardiology
Volume 135, Issue 2 , Pages 238-239, 26 June 2009

Bradycardia and B-type natriuretic peptide

St. John of God Hospital, Budapest, Hungary

Received 25 March 2008; accepted 29 March 2008. published online 07 July 2008.

Abstract 

Bradycardia and loss of atrioventricular synchrony can result inincreased natriuretic peptide secretion due to increased cardiac wall tension. Antihypertensive beta-blocker therapy has been shown to cause elevated natriuretic peptide levels, as well as to increase the frequency of atrial fibrillation in hypertensive patients. The measurement of natriuretic peptides might help solve the clinical challenge of predicting the patients with high risk for beta-blocker induced atrial fibrillation.

Keywords: B-type natriuretic peptide, BNP, Bradycardia, Hypertension, Atrioventricular synchrony

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PII: S0167-5273(08)00562-7

doi:10.1016/j.ijcard.2008.03.086

International Journal of Cardiology
Volume 135, Issue 2 , Pages 238-239, 26 June 2009