International Journal of Cardiology
Volume 136, Issue 2 , Pages 130-135 , 14 August 2009

Inducibility of atrial fibrillation during electrophysiologic evaluation is associated with increased dispersion of atrial refractoriness

  • Mario Oliveira

      Affiliations

    • Cardiology Department, Santa Marta Hospital, Lisbon, Portugal
    • Corresponding Author InformationCorresponding author.
    • ,
  • M. Nogueira da Silva

      Affiliations

    • Cardiology Department, Santa Marta Hospital, Lisbon, Portugal
    • ,
  • Ana T. Timoteo

      Affiliations

    • Cardiology Department, Santa Marta Hospital, Lisbon, Portugal
    • ,
  • Joana Feliciano

      Affiliations

    • Cardiology Department, Santa Marta Hospital, Lisbon, Portugal
    • ,
  • Lidia Sousa

      Affiliations

    • Cardiology Department, Santa Marta Hospital, Lisbon, Portugal
    • ,
  • Sofia Santos

      Affiliations

    • Cardiology Department, Santa Marta Hospital, Lisbon, Portugal
    • ,
  • Luis Silva-Carvalho

      Affiliations

    • Institute of Physiology, Faculty of Medicine of Lisbon, Portugal
    • ,
  • Rui Ferreira

      Affiliations

    • Cardiology Department, Santa Marta Hospital, Lisbon, Portugal

Received 7 September 2007 ,Revised 20 March 2008 ,Accepted 23 April 2008.

References 

  1. Camm AJ. Preface. In:  Murgatroyd, FD,  Camm, AJ editor. Nonpharmacological Treatment of Atrial Fibrillation. Armonk, NY: Futura; 1997;
  2. Feinberg WM, Blackshear JL, Laupacis A, et al. Prevalence, age distributions, and gender of patients with atrial fibrillation: analysis and implications. Arch Intern Med. 1995;155:469–473
  3. Benjamin EJ, Wolf PA, D'Agostino RB, et al. Impact of atrial fibrillation on the risk of death. The Framinghan Heart Study. Circulation. 1998;98:946–952
  4. Van Den Berg MP, Hassink RJ, Tuinenburg AE, Van Sonderen EF, Lefrandt JD, et al. Quality of life in patients with paroxysmal atrial fibrillation and its predictors: importance of the autonomic nervous system. Eur Heart J. 2001;22:247–253
  5. Peters NS, Schilling RJ, Kanagaratnam P, Markides V. Atrial fibrillation: strategies to control, combat, and cure. Lancet. 2002;359(9306):593–603
  6. Kopecky SL, Gersh BJ, McGoon MD, et al. The natural history of lone atrial fibrillation. A population-based study over three decades. N Engl J Med. 1987;317:669–674
  7. Soylu M, Demir AD, Özdemir Ö, et al. Increased dispersion of refractoriness in patients with atrial fibrillation in the early postoperative period after coronary artery bypass grafting. J Cardiovasc Electrophysiol. January 2003;14:28–31
  8. Wang L, Yang H, Zhang Y. Recurrence of symptomatic atrial fibrillation after successful catheter ablation of atrioventricular accessory pathways: a multivariate regression analysis. Int J Clin Pract. August 2005;59(8):886
  9. Richter B, Gwechenberger M, Filzmoser P, Marx M, Lercher P, Gossinger HD. Is inducibility of atrial fibrillation after radio frequency ablation really a relevant prognostic factor?. Eur Heart J. Nov 2006;27(21):2553–2559
  10. Nattel S, Li D, Yue L. Basic mechanisms of atrial fibrillation—very new insights into very old ideas. Annu Rev Physiol. 2000;62:51–77
  11. Li Zhen, Hertervig Eva, Carlson Jonas, Camilla J, Bertil O, Yuan S. Dispersion of refractoriness in patients with paroxysmal atrial fibrillation. Evaluation with simultaneous endocardial recordings from both atria. J Electrocardiol. 2002;35(3):227–234
  12. Chen J, Wasmund SL, Hamdan MH. Back to the future: the role of the autonomic nervous system in atrial fibrillation. Pacing Clin Electrophysiol. 2006;29:413–421
  13. Misier A, Opthof T, van Hemel N, et al. Increased dispersion of “refractoriness” in patients with idiopathic paroxysmal atrial fibrillation. J Am Coll Cardiol. 1992;19:1531–1535
  14. Sato S, Yamauchi S, Schuessler RB, et al. The effect of augmented atrial hypothermia on atrial refractory period, conduction, and atrial flutter/fibrillation in the canine heart. J Thorac Cardiovasc Surg. 1992;104:297–306
  15. Rahme MM, Cotter B, Leistad E, et al. Persistence of atrial fibrillation after its induction—importance of the duration and dispersion of atrial refractoriness and electrical remodeling. J Cardiovasc Pharmacol Ther. Apr 1999;4(2):113–120
  16. Friedman HS, Sinha B, Tun A, et al. Zones of atrial vulnerability. Relationships to basic cycle length. Circulation. 1996;94:1456–1464
  17. Yu WC, Chen SA, Lee SH, Tai CT, et al. Tachycardia-induced change of atrial refractory period in humans. Rate dependency and effects of antiarrhythmic drugs. Circulation. 1998;97:2331–2337
  18. Daoud EG, Bogum F, Goyal R, Harvey M, Man KC, Strickberger SA, et al. Effect of atrial fibrillation on atrial refractoriness in humans. Circulation. 1996;94:1600–1606
  19. Goette A, Honeycutt C, Langberg JJ. Electrical remodeling in atrial fibrillation: time course and mechanisms. Circulation. 1996;94:2968–2974
  20. Byrd GD, Prasad SM, Ripplinger CM, et al. Importance of geometry and refractory period in sustaining atrial fibrillation. Testing the critical mass hypothesis. Circulation. 2005;112:I–7 – I-13
  21. Ishimatsu T, Hayano M, Hirata T, Iliev II, et al. Electrophysiological properties of the left atrium evaluated by coronary sinus pacing in patients with atrial fibrillation. Pacing Clin Electrophysiol. Dec 1999;22(12):1739–1746
  22. Zipes DP, Mihalick MJ, Robbins GT. Effects of selective vagal and stellate ganglion stimulation on atrial refractoriness. Cardiovasc Res. 1974;8:647–655
  23. Li Z, Hertervig E, Yuan S, Yang Y, Lin Z, Olsson BS. Dispersion of atrial repolarization in patients with paroxysmal atrial fibrillation. Europace. 2001;3:285–291
  24. Olgin JE, Sih HJ, Hanish S, Jayachandran JV, et al. Heterogeneous atrial denervation creates substrate for sustained atrial fibrillation. Circulation. Dec 8 1998;98(23):2608–2614
  25. Wang J, Liu L, Feng J, Nattel S. Regional and functional factors determining induction and maintenance of atrial fibrillation in dogs. Am J Physiol. 1996;271:H148–H158
  26. Allessie MA, Bonke FI, Schopman FJ. Circus movement in rabbit atrial muscle as a mechanism of tachycardia. The “leading circle” concept: a new model of circus movement in cardiac tissue without the involvement of an anatomical obstacle. Circ Res. 1977;41:9–18
  27. Schilling RJ, Kadish AH, Peters N, et al. Endocardial mapping of atrial fibrillation in the human right atrium using a non-contact catheter. Eur Heart J. 2000;21:550–564
  28. Allessie MA, Konings K, Kirchhof CJ, Wijffels M. Electrophysiologic mechanisms of perpetuation of atrial fibrillation. Am J Cardiol. 1996;77:10A–23A
  29. Adragao P, Santos K, Aguiar C, Neves J, Abecassis M, et al. Atrial fibrillation and effective refractory period of the pulmonary vein ostia. Rev Port Cardiol. Oct 2002;21(10):1125–1134
  30. Jais P, Hocini M, Macle L, Choi KJ, Deisenhofer I, Weerasooriya R, et al. Distinctive electrophysiological properties of pulmonary veins in patients with atrial fibrillation. Circulation. Nov 5 2002;106(19):2479–2485
  31. Mandapati R, Skanes A, Chen J, Berenfeld O, Jalife J. Stable micro re-entrant sources as a mechanism of atrial fibrillation in the isolated sheep heart. Circulation. 2000;101:194–199
  32. Haissaguerre M, Hocini M, Sanders P, Takahashi Y, et al. Localized sources maintaining atrial fibrillation organized by prior ablation. Circulation. Feb 7 2006;113(5):616–625
  33. Chen M, Guo GB, Chang HW. Atrial electrophysiological properties evaluated by right and left atrial pacing in patients with or without atrial fibrillation. Jpn Heart J. 2002;43:231–240

PII: S0167-5273(08)00613-X

doi: 10.1016/j.ijcard.2008.04.097

International Journal of Cardiology
Volume 136, Issue 2 , Pages 130-135 , 14 August 2009

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