International Journal of Cardiology
Volume 131, Issue 2 , Pages 180-185, 9 January 2009

‘Lone’ atrial fibrillation: Hunting for the underlying causes and links

  • Panagiotis Korantzopoulos

      Affiliations

    • Department of Cardiology, University of Ioannina School of Medicine, Ioannina, Greece
    • Corresponding Author InformationCorresponding author. Tel.: +30 26510 99347; fax: +30 26510 97017.
    • ,
  • Tong Liu

      Affiliations

    • Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, People's Republic of China
    • ,
  • Haralampos J. Milionis

      Affiliations

    • Department of Internal Medicine, University of Ioannina School of Medicine, Ioannina, Greece
    • ,
  • Guangping Li

      Affiliations

    • Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, People's Republic of China
    • ,
  • John A. Goudevenos

      Affiliations

    • Department of Cardiology, University of Ioannina School of Medicine, Ioannina, Greece

Received 15 January 2008; received in revised form 27 April 2008; accepted 28 June 2008. published online 08 August 2008.

Abstract 

The presence of lone atrial fibrillation presupposes the absence of structural heart disease, hypertension, or other known predisposing factors. However, several recent clinical and experimental data provide novel insights into the pathogenesis of lone atrial fibrillation. In addition, modern diagnostic techniques often reveal some previously unappreciated abnormalities. Therefore, the increasing recognition of potential causes and links sets the base for a more complete elucidation of its etiology in the near future. This concise review article discusses the contemporary advances in the understanding of this form of atrial fibrillation.

Keywords: Lone atrial fibrillation, Etiology, Pathophysiology, Pathogenesis, Epidemiology, Genetics

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PII: S0167-5273(08)00830-9

doi:10.1016/j.ijcard.2008.06.035

International Journal of Cardiology
Volume 131, Issue 2 , Pages 180-185, 9 January 2009

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