International Journal of Cardiology
Volume 144, Issue 1 , Pages 163-165 , 24 September 2010

Concomitant insulin resistance and impaired vascular function is associated with increased coronary artery calcification

  • Naser Ahmadi

      Affiliations

    • Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, USA
    • ,
  • Sumithra Tirunagaram

      Affiliations

    • Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, USA
    • ,
  • Fereshteh Hajsadeghi

      Affiliations

    • Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, USA
    • ,
  • Ferdinand Flores

      Affiliations

    • Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, USA
    • ,
  • Anila Saeed

      Affiliations

    • Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, USA
    • ,
  • Harvey Hecht

      Affiliations

    • Lenox Hill Heart & Vascular Institute, New York, NY, USA
    • ,
  • Morteza Naghavi

      Affiliations

    • Society for Heart Attack Prevention and Eradication, Houston, TX, USA
    • ,
  • Matthew Budoff

      Affiliations

    • Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, USA
    • Corresponding Author InformationCorresponding author. Harbor-UCLA Medical Center, 1124 W. Carson Street, RB2, Torrance, CA 90502, USA. Tel.: +1 310 222 4107; fax: +1 310 787 0448.

Received 3 December 2008 ,Accepted 14 December 2008.

References 

  1. Montecucco F, Steffens S, Mach F. Insulin resistance: a proinflammatory state mediated by lipid-induced signaling dysfunction and involved in atherosclerotic plaque instability. Mediators Inflamm. 2008;2008:767623
  2. Li C, Ford ES, Meng YX, Mokdad AH, Reaven GM. Does the association of the triglyceride to high-density lipoprotein cholesterol ratio with fasting serum insulin differ by race/ethnicity?. Cardiovasc Diabetol. Feb 28 2008;7:4
  3. Wilson PWF, D'Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB. Prediction of coronary heart disease using risk factor categories. Circulation. 1998;97:1837–1847
  4. Becker CR, Knez A, Jakobs TF, et al. Detection and quantification of coronary artery calcification with electron-beam and conventional CT. Eur Radiol. 1999;9(4):620–624
  5. Frohlich J, Dobiasova M. Fractional esterification rate of cholesterol and ratio of triglycerides to HDL-cholesterol are powerful predictors of positive findings on coronary angiography. Clin Chem. 2003;49:1873–1880
  6. Gaziano JM, Hennekens CH, O'Donnell CJ, Breslow JL, Buring JE. Fasting triglycerides, high-density lipoprotein, and risk of myocardial infarction. Circulation. 1997;96:2520–2525
  7. Dobiasova M, Frohlich J. The plasma parameter log (TG/HDL-C) as an atherogenic index: correlation with lipoprotein particle size and esterification rate in apoB-lipoprotein-depleted plasma (FERHDL). Clin Biochem. 2001;34:583–588F
  8. Dobiasova M. Atherogenic index of plasma [log(triglycerides/HDL-cholesterol)]: theoretical and practical implications. Clin Chem. 2004;50:1113–1115
  9. Jeppesen J, Hein HO, Suadicani P, Gyntelberg F. Low triglycerides-high high-density lipoprotein cholesterol and risk of ischemic heart disease. Arch Intern Med. 2001;161:361–366
  10. Detrano R, Guerci AD, Carr JJ, et al. Coronary calcium as a predictor of coronary events in four racial or ethnic groups. N Engl J Med. Mar 27 2008;358(13):1336–1345
  11. Coats AJ. Ethical authorship and publishing. Int J Cardiol. 2009;131:149–150

PII: S0167-5273(08)01583-0

doi: 10.1016/j.ijcard.2008.12.200

International Journal of Cardiology
Volume 144, Issue 1 , Pages 163-165 , 24 September 2010

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