International Journal of Cardiology
Volume 152, Issue 2 , Pages 202-206, 20 October 2011

Enhancement of ultrasonic thrombus imaging using novel liposomal bubbles targeting activated platelet glycoprotein IIb/IIIa complex—in vitro and in vivo study

  • Kohsuke Hagisawa

      Affiliations

    • Department of Medical Engineering, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan
  • ,
  • Toshihiko Nishioka

      Affiliations

    • Division of Cardiology, Saitama Medical Center, Saitama Medical University, 1981 Kamoda, Kawagoe, Saitama 350-8550, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81 49 228 3587; fax: +81 49 226 5274.
  • ,
  • Ryo Suzuki

      Affiliations

    • Department of Biopharmaceutics, School of Pharmaceutical Science, Teikyo University, 1091-1 Suwarashi, Sagamiko, Sagamihara, Kanagawa 229-0195, Japan
  • ,
  • Tomoko Takizawa

      Affiliations

    • Department of Biopharmaceutics, School of Pharmaceutical Science, Teikyo University, 1091-1 Suwarashi, Sagamiko, Sagamihara, Kanagawa 229-0195, Japan
  • ,
  • Kazuo Maruyama

      Affiliations

    • Department of Biopharmaceutics, School of Pharmaceutical Science, Teikyo University, 1091-1 Suwarashi, Sagamiko, Sagamihara, Kanagawa 229-0195, Japan
  • ,
  • Bonpei Takase

      Affiliations

    • Division of Biomedical Engineering, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan
  • ,
  • Masayuki Ishihara

      Affiliations

    • Division of Biomedical Engineering, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan
  • ,
  • Akira Kurita

      Affiliations

    • Division of Biomedical Engineering, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan
  • ,
  • Nobuo Yoshimoto

      Affiliations

    • Division of Cardiology, Saitama Medical Center, Saitama Medical University, 1981 Kamoda, Kawagoe, Saitama 350-8550, Japan
  • ,
  • Fumitaka Ohsuzu

      Affiliations

    • First Department of Internal Medicine, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan
  • ,
  • Makoto Kikuchi

      Affiliations

    • Department of Medical Engineering, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan

Received 12 February 2010; received in revised form 19 June 2010; accepted 4 July 2010. published online 02 August 2010.

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PII: S0167-5273(10)00543-7

doi:10.1016/j.ijcard.2010.07.016

International Journal of Cardiology
Volume 152, Issue 2 , Pages 202-206, 20 October 2011