International Journal of Cardiology
Volume 152, Issue 2 , Pages 231-236 , 20 October 2011

Time course of markers of tissue repair after ablation of atrial fibrillation and their relation to left atrial structural changes and clinical ablation outcome

  • Bernhard Richter

      Affiliations

    • Department of Cardiology, Medical University of Vienna, Vienna, Austria
    • Corresponding Author InformationCorresponding author. Department of Cardiology, Medical University of Vienna, Währinger Gürtel 18-20, A-1090 Vienna, Austria, Tel.: +43 1404004614; fax: +43 1404004216.
    • ,
  • Marianne Gwechenberger

      Affiliations

    • Department of Cardiology, Medical University of Vienna, Vienna, Austria
    • ,
  • Ariel Socas

      Affiliations

    • Department of Cardiology, Medical University of Vienna, Vienna, Austria
    • ,
  • Gerlinde Zorn

      Affiliations

    • Department of Cardiology, Medical University of Vienna, Vienna, Austria
    • ,
  • Sulaima Albinni

      Affiliations

    • Department of Paediatric Cardiology, Medical University of Vienna, Vienna, Austria
    • ,
  • Manfred Marx

      Affiliations

    • Department of Paediatric Cardiology, Medical University of Vienna, Vienna, Austria
    • ,
  • Florian Wolf

      Affiliations

    • Department of Radiology, Medical University of Vienna, Vienna, Austria
    • ,
  • Jutta Bergler-Klein

      Affiliations

    • Department of Cardiology, Medical University of Vienna, Vienna, Austria
    • ,
  • Christian Loewe

      Affiliations

    • Department of Radiology, Medical University of Vienna, Vienna, Austria
    • ,
  • Christian Bieglmayer

      Affiliations

    • Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria
    • ,
  • Thomas Binder

      Affiliations

    • Department of Cardiology, Medical University of Vienna, Vienna, Austria
    • ,
  • Johann Wojta

      Affiliations

    • Department of Cardiology, Medical University of Vienna, Vienna, Austria
    • ,
  • Heinz D. Gössinger

      Affiliations

    • Department of Cardiology, Medical University of Vienna, Vienna, Austria

Received 9 February 2010 ,Revised 23 May 2010 ,Accepted 4 July 2010.

References 

  1. Gharaee-Kermani M, Phan SH. Role of cytokines and cytokine therapy in wound healing and fibrotic diseases. Curr Pharm Des. 2001;7:1083–1103
  2. Frangogiannis NG. The mechanistic basis of infarct healing. Antioxid Redox Signal. 2006;8:1907–1939
  3. Badger TJ, Oakes RS, Daccarett M, et al. Temporal left atrial lesion formation after ablation of atrial fibrillation. Heart Rhythm. 2009;6:161–168
  4. Ulrich D, Noah EM, Burchardt ER, Atkins D, Pallua N. Serum concentration of amino-terminal propeptide of type III procollagen (PIIINP) as a prognostic marker for skin fibrosis after scar correction in burned patients. Burns. 2002;28:766–771
  5. Jensen LT, Horslev-Petersen K, Toft P, et al. Serum aminoterminal type III procollagen peptide reflects repair after acute myocardial infarction. Circulation. 1990;81:52–57
  6. Creemers EE, Cleutjens JP, Smits JF, Daemen MJ. Matrix metalloproteinase inhibition after myocardial infarction: a new approach to prevent heart failure?. Circ Res. 2001;89:201–210
  7. Varedi M, Jeschke MG, Englander EW, Herndon DN, Barrow RE. Serum TGF-beta in thermally injured rats. Shock. 2001;16:380–382
  8. Kaden JJ, Dempfle CE, Sueselbeck T, et al. Time-dependent changes in the plasma concentration of matrix metalloproteinase 9 after acute myocardial infarction. Cardiology. 2003;99:140–144
  9. Ulrich D, Noah EM, von Heimburg D, Pallua N. TIMP-1, MMP-2, MMP-9, and PIIINP as serum markers for skin fibrosis in patients following severe burn trauma. Plast Reconstr Surg. 2003;111:1423–1431
  10. Calkins H, Brugada J, Packer DL, et al. HRS/EHRA/ECAS expert Consensus Statement on catheter and surgical ablation of atrial fibrillation: recommendations for personnel, policy, procedures and follow-up. A report of the Heart Rhythm Society (HRS) Task Force on catheter and surgical ablation of atrial fibrillation. Heart Rhythm. 2007;4:816–861
  11. Kircher B, Abbott JA, Pau S, et al. Left atrial volume determination by biplane two-dimensional echocardiography: validation by cine computed tomography. Am Heart J. 1991;121:864–871
  12. Savelieva I, Camm J. Statins and polyunsaturated fatty acids for treatment of atrial fibrillation. Nat Clin Pract Cardiovasc Med. 2008;5:30–41
  13. Brueckmann M, Wolpert C, Bertsch T, et al. Markers of myocardial damage, tissue healing, and inflammation after radiofrequency catheter ablation of atrial tachyarrhythmias. J Cardiovasc Electrophysiol. 2004;15:686–691
  14. Nakano Y, Niida S, Dote K, et al. Matrix metalloproteinase-9 contributes to human atrial remodeling during atrial fibrillation. J Am Coll Cardiol. 2004;43:818–825
  15. Kourliouros A, Savelieva I, Kiotsekoglou A, Jahangiri M, Camm J. Current concepts in the pathogenesis of atrial fibrillation. Am Heart J. 2009;157:243–252
  16. Reant P, Lafitte S, Jais P, et al. Reverse remodeling of the left cardiac chambers after catheter ablation after 1year in a series of patients with isolated atrial fibrillation. Circulation. 2005;112:2896–2903
  17. Muller H, Noble S, Keller PF, et al. Biatrial anatomical reverse remodelling after radiofrequency catheter ablation for atrial fibrillation: evidence from real-time three-dimensional echocardiography. Europace. 2008;10:1073–1078
  18. Avitall B, Urbonas A, Urboniene D, Millard S, Helms R. Time course of left atrial mechanical recovery after linear lesions: normal sinus rhythm versus a chronic atrial fibrillation dog model. J Cardiovasc Electrophysiol. 2000;11:1397–1406
  19. Jayam VK, Dong J, Vasamreddy CR, et al. Atrial volume reduction following catheter ablation of atrial fibrillation and relation to reduction in pulmonary vein size: an evaluation using magnetic resonance angiography. J Interv Card Electrophysiol. 2005;13:107–114
  20. Tops LF, Bax JJ, Zeppenfeld K, Jongbloed MR, van der Wall EE, Schalij MJ. Effect of radiofrequency catheter ablation for atrial fibrillation on left atrial cavity size. Am J Cardiol. 2006;97:1220–1222
  21. Phatharajaree W, Phrommintikul A, Chattipakorn N. Matrix metalloproteinases and myocardial infarction. Can J Cardiol. 2007;23:727–733
  22. Roldan V, Marin F, Gimeno JR, et al. Matrix metalloproteinases and tissue remodeling in hypertrophic cardiomyopathy. Am Heart J. 2008;156:85–91
  23. Nagy Z, Czirjak L. Increased levels of amino terminal propeptide of type III procollagen are an unfavourable predictor of survival in systemic sclerosis. Clin Exp Rheumatol. 2005;23:165–172
  24. Lammi L, Ryhanen L, Lakari E, et al. Type III and type I procollagen markers in fibrosing alveolitis. Am J Respir Crit Care Med. 1999;159:818–823
  25. Nojgaard C, Johansen JS, Christensen E, Skovgaard LT, Price PA, Becker U. Serum levels of YKL-40 and PIIINP as prognostic markers in patients with alcoholic liver disease. J Hepatol. 2003;39:179–186
  26. Jensen LT, Host NB. Collagen: scaffold for repair or execution. Cardiovasc Res. 1997;33:535–539
  27. Kurdy NM. Serology of abnormal fracture healing: the role of PIIINP, PICP, and BsALP. J Orthop Trauma. 2000;14:48–53
  28. Gangemi EN, Gregori D, Berchialla P, et al. Epidemiology and risk factors for pathologic scarring after burn wounds. Arch Facial Plast Surg. 2008;10:93–102
  29. Seifert O, Mrowietz U. Keloid scarring: bench and bedside. Arch Dermatol Res. 2009;301:259–272
  30. Poulsen SH, Host NB, Jensen SE, Egstrup K. Relationship between serum amino-terminal propeptide of type III procollagen and changes of left ventricular function after acute myocardial infarction. Circulation. 2000;101:1527–1532
  31. Host NB, Jensen LT, Bendixen PM, Jensen SE, Koldkjaer OG, Simonsen EE. The aminoterminal propeptide of type III procollagen provides new information on prognosis after acute myocardial infarction. Am J Cardiol. 1995;76:869–873
  32. Ouyang F, Antz M, Ernst S, et al. Recovered pulmonary vein conduction as a dominant factor for recurrent atrial tachyarrhythmias after complete circular isolation of the pulmonary veins: lessons from double Lasso technique. Circulation. 2005;111:127–135
  33. Boos CJ, Anderson RA, Lip GY. Is atrial fibrillation an inflammatory disorder?. Eur Heart J. 2006;27:136–149
  34. Burstein B, Nattel S. Atrial structural remodeling as an antiarrhythmic target. J Cardiovasc Pharmacol. 2008;52:4–10
  35. Liu T, Li L, Korantzopoulos P, Liu E, Li G. Statin use and development of atrial fibrillation: a systematic review and meta-analysis of randomized clinical trials and observational studies. Int J Cardiol. 2008;126:160–170
  36. Coats AJ. Ethical authorship and publishing. Int J Cardiol. 2009;131:149–150

☆ Grant support: The study was funded by the Medical-Scientific Fund of the Mayor of the City of Vienna (Vienna, Austria). The study was also supported by a research fund provided by Biosense Webster (Diamond Bar, CA, USA).

PII: S0167-5273(10)00548-6

doi: 10.1016/j.ijcard.2010.07.021

International Journal of Cardiology
Volume 152, Issue 2 , Pages 231-236 , 20 October 2011

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