Atherosclerosis is an inflammatory disease [
[1]
]. Key evidence of this is the initial influx of monocytes and T-lymphocytes into the
vessel wall in response to injury to the endothelium. Mediators of this migration
are probably crucial in plaque development, but remain largely undefined. Potential
offenders include, however, chemokines — a superfamily group of chemotactic cytokines.
In this issue, Economou et al. highlight the potential atherogenic role of one of
these substances — monocyte chemoattractant protein 1 (MCP-1).To read this article in full you will need to make a payment
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References
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Article info
Footnotes
☆This is an Editorial comment to a paper published as Int. J. Cardiol. 2001;80:55.
Identification
Copyright
© 2001 Elsevier Science B.V. Published by Elsevier Inc. All rights reserved.
