Abstract
In patients with panic disorder, an anxiety disorder, isoproterenol increases beat-to-beat
QRS amplitude variability much more than in normal controls. In this pilot study,
we found that patients with panic disorder had significantly higher beat-to-beat QRS
amplitude variability compared to controls in resting supine and standing postures.
This may be partly due to myocardial electrical instability or irregular respiration
in this patient group. These findings are important in view of the association between
panic disorder and increased cardiovascular mortality.
Keywords
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Article info
Publication history
Published online: December 22, 2008
Accepted:
December 3,
2008
Received in revised form:
November 30,
2008
Received:
July 8,
2008
Identification
Copyright
© 2008 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
