Letter to the Editor| Volume 145, ISSUE 3, P497, December 03, 2010

Consensus on unsolved issues of left ventricular hypertrabeculation/noncompaction is warranted

Published:November 09, 2009DOI:


      As long as there is no consensus on the definition, diagnostic criteria, and pathogenesis of left ventricular hypertrabeculation (LVHT)/noncompaction misdiagnosis, overreaction, and mistreatment of this abnormality will eventually continue. When considering a therapy for patients presenting with LVHT it has to be taken into account that LVHT is not associated with an increased risk of thrombo-embolism in the absence of atrial fibrillation or systolic dysfunction. There is also no proof that the degree of LVHT correlates with the degree of systolic dysfunction. Secondary prevention of stroke/embolism and sudden cardiac death is indicated in LVHT only if cardiac investigations reveal atrial fibrillation, systolic dysfunction, or ventricular arrhythmias. Up to what we know at the moment LVHT patients should be closely monitored by conventional cardiologic and neurologic diagnostic tools and appropriate measures taken, only if indicated.


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