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Reply to manuscript IJC-D-12-04197 entitled “Does alpha-lipoic acid treatment play a role on oxidative stress and insulin resistance in overweight/obese patients?” by MD Turgay Ulas

Published:January 14, 2013DOI:https://doi.org/10.1016/j.ijcard.2012.12.034
      We greatly appreciate the thoughtful comments by Dr. Turgay Ulas [
      • Ulas T.
      • Hacıbekiroglu T.
      • Karakas E.Y.
      • Yildiz A.
      Does alpha-lipoic acid treatment play a role on oxidative stress and insulin resistance in overweight/obese patients?.
      ] on our study [
      • Yan W.
      • Li N.
      • Hu X.
      • et al.
      Effect of oral ALA supplementation on oxidative stress and insulin sensitivity among overweight/obese adults: a double-blinded, randomized, controlled, cross-over intervention trial.
      ], which makes two points: first, the use of HOMA-IR in defining insulin resistance; and second, the limitation in selection of two oxidative stress biomarkers. We would like to respond to each of the points delineated by Dr. Ulas.

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      References

        • Ulas T.
        • Hacıbekiroglu T.
        • Karakas E.Y.
        • Yildiz A.
        Does alpha-lipoic acid treatment play a role on oxidative stress and insulin resistance in overweight/obese patients?.
        Int J Cardiol. Nov 28 2012; https://doi.org/10.1016/j.ijcard.2012.11.107
        • Yan W.
        • Li N.
        • Hu X.
        • et al.
        Effect of oral ALA supplementation on oxidative stress and insulin sensitivity among overweight/obese adults: a double-blinded, randomized, controlled, cross-over intervention trial.
        Int J Cardiol. 2013; 167: 602-603
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