Advertisement

Health-related quality of life associated with treatment adherence in patients with hypertension: A cross-sectional study

      Hypertension is one of the most important risk factors for coronary heart disease, heart failure, renal failure and stroke, and it remains an important public health challenge which contributes to disability, health care costs and mortality [
      • Stein A.D.
      • Stoyanovsky V.
      • Mincheva V.
      • et al.
      Prevalence, awareness, treatment and control of hypertension in a working Bulgarian population.
      ,
      • Ong K.L.
      • Cheung B.M.Y.
      • Man Y.B.
      • Lau C.P.
      • Lam K.S.L.
      Prevalence, awareness, treatment, and control of hypertension among United States adults 1999–2004.
      ]. The concepts of medication adherence and health-related quality of life (HRQoL) are commonly used in clinical research for assessing pharmaceutical care and improving treatment outcomes [
      • Côté I.
      • Farris K.
      • Feeny D.
      Is adherence to drug treatment correlated with health-related quality of life?.
      ]. Adherence to drug treatment usually refers to the extent to which patients follow the instructions of their physician or health care providers. HRQoL also refers to the physical, psychological and social dimensions of health that are influenced by a person's experiences, beliefs, expectations and perceptions [
      • Chen H.
      • Taichman D.B.
      • Doyle R.L.
      Health-related quality of life and patient-reported outcomes in pulmonary arterial hypertension.
      ]. Generally one would expect a positive relationship between the two concepts. The objective of this study was to examine the relationship between adherence and HRQoL in a hypertensive population. Knowledge of any differences in HRQoL in this population may be helpful in the planning of therapeutic interventions that will ensure desirable HRQoL and not just the control of blood pressure. Knowledge of HRQoL in hypertensive patients and of the relationship between HRQoL and adherence, being a reliable determinant of cardiovascular disease (CVD) events, will be helpful in preventing or reducing the incidence of CVDs.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to International Journal of Cardiology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Stein A.D.
        • Stoyanovsky V.
        • Mincheva V.
        • et al.
        Prevalence, awareness, treatment and control of hypertension in a working Bulgarian population.
        Eur J Epidemiol. 2000; 16: 265-270
        • Ong K.L.
        • Cheung B.M.Y.
        • Man Y.B.
        • Lau C.P.
        • Lam K.S.L.
        Prevalence, awareness, treatment, and control of hypertension among United States adults 1999–2004.
        Hypertension. 2007; 49: 69-75
        • Côté I.
        • Farris K.
        • Feeny D.
        Is adherence to drug treatment correlated with health-related quality of life?.
        Qual Life Res. 2003; 12: 621-633
        • Chen H.
        • Taichman D.B.
        • Doyle R.L.
        Health-related quality of life and patient-reported outcomes in pulmonary arterial hypertension.
        Proc Am Thorac Soc. 2008; 5: 623-630
        • Morisky D.E.
        • Green L.W.
        • Levine D.M.
        Concurrent and predictive validity of a self-reported measure of medication adherence.
        Med Care. 1986; : 67-74
        • Morisky D.E.
        • Ang A.
        • Krousel-Wood M.
        • Ward H.J.
        Predictive validity of a medication adherence measure in an outpatient setting.
        J Clin Hypertens (Greenwich). 2008; 10: 348-354
        • EuroQOL Group
        EQ-5D-5L user guide: basic information on how to use the EQ-5D-5L instrument. 2011