Coronary slow flow phenomenon first described by Tambe et al. in 1972, is a coronary
microvascular disorder characterized by the delayed passage of contrast in the absence
of obstructive epicardial coronary disease [
1
,
2
]. Quantitatively, it is measured as increased Thrombolysis in Myocardial Infarction
(TIMI) frame count. TIMI frame count, introduced by Gibson [
[3]
], is a reproducible index of coronary flow. Although the exact processes are not known
well yet, microvascular dysfunction or abnormal vasomotion is one of the most forthcoming
mechanism underlying SCF phenomenon [
2
,
4
,
5
,
6
,
7
,
8
,
9
,
10
]. Anxiety and depression has been shown to be associated with increased risk of cardiovascular
events, progression of atherosclerosis and death [
[11]
]. Accordingly we aimed to assess the possible relation of patients' anxiety and depression
status on coronary flow pattern in patients with angiographically normal coronary
arteries, and slow coronary flow phenomenon.- Lichtman J.H.
- Bigger Jr., J.T.
- Blumenthal J.A.
- Frasure-Smith N.
- Kaufmann P.G.
- Lesperance F.
- Mark D.B.
- Sheps D.S.
- Taylor C.B.
- Froelicher E.S.
- American Heart Association Prevention Committee of the Council on Cardiovasculer Nursing
- American Heart Association Council on Clinical Cardiology
- American Heart Association Council on Epidemiology, Prevention
- American Heart Association Interdisciplinary Council on Quality of Care and Outcomes Research
- American Psychiatric Association
Depression and coronary heart disease: recommendations for screening, referral, and
treatment: a science advisory from the American Heart Association Prevention Committee
of the Council on Cardiovascular Nursing, Council on Clinical Cardiology, Council
on Epidemiology and Prevention, and Interdisciplinary Council on Quality of Care and
Outcomes Research: endorsed by the American Psychiatric Association.
Circulation. 2008; 118: 1768-1775
Keywords
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Article info
Publication history
Published online: November 25, 2014
Accepted:
November 22,
2014
Received:
November 8,
2014
Identification
Copyright
© 2014 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
