Timely performed reperfusion and adjuvant drug therapy are essential in the treatment
of acute ST elevation myocardial infarction (STEMI). Reperfusion of the infarct-related
artery (IRA) may, paradoxically, result in further injury of the ischemic myocardium
by mechanisms collectively termed ischemia/reperfusion (I/R) injury [
[1]
]. Cardioprotection by ischemic postconditioning (IPost), performed by interrupted
blood-flow to the ischemic myocardium at the time of reperfusion, has shown diverging
effects on measures of infarct size and left ventricular (LV) function in clinical
trials [
[2]
]. Previous studies have shown good correlation between myocardial strain measured
by 2-dimensional (2-D) speckle tracking echocardiography and infarct size and LV function
[
[3]
]. Furthermore, post-systolic shortening has been suggested to be associated with ischemic
segments with potential for recovery in patients with non-STEMI [
[4]
]. However, little is known about a possible effect of IPost on myocardial strain in
the acute stage of STEMI.Keywords
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References
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Article info
Publication history
Published online: March 19, 2015
Accepted:
March 17,
2015
Received:
February 11,
2015
Identification
Copyright
© 2015 Published by Elsevier Inc.
