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Variations in cardiovascular risk factors in people with and without migration background in Germany – Results from the STAAB cohort study

  • Author Footnotes
    1 This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.
    Caroline Morbach
    Footnotes
    1 This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.
    Affiliations
    Comprehensive Heart Failure Center and Dept. of Medicine I, University Hospital and University of Würzburg, Germany
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  • Author Footnotes
    1 This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.
    Götz Gelbrich
    Footnotes
    1 This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.
    Affiliations
    Institute of Clinical Epidemiology and Biometry and Comprehensive Heart Failure Center, University of Würzburg, Germany
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  • Author Footnotes
    1 This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.
    Theresa Tiffe
    Footnotes
    1 This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.
    Affiliations
    Institute of Clinical Epidemiology and Biometry and Comprehensive Heart Failure Center, University of Würzburg, Germany
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  • Author Footnotes
    1 This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.
    Felizitas Eichner
    Footnotes
    1 This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.
    Affiliations
    Institute of Clinical Epidemiology and Biometry and Comprehensive Heart Failure Center, University of Würzburg, Germany
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  • Author Footnotes
    1 This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.
    Martin Wagner
    Footnotes
    1 This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.
    Affiliations
    Institute of Clinical Epidemiology and Biometry and Comprehensive Heart Failure Center, University of Würzburg, Germany
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  • Author Footnotes
    1 This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.
    ,
    Author Footnotes
    2 Both authors contributed equally.
    Peter U. Heuschmann
    Footnotes
    1 This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.
    2 Both authors contributed equally.
    Affiliations
    Institute of Clinical Epidemiology and Biometry, Comprehensive Heart Failure Center, and Clinical Trial Center, University of Würzburg, Germany
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  • Author Footnotes
    1 This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.
    ,
    Author Footnotes
    2 Both authors contributed equally.
    Stefan Störk
    Correspondence
    Corresponding author at: Comprehensive Heart Failure Center Würzburg, Am Schwarzenberg 15, D – 97078 Würzburg, Germany.
    Footnotes
    1 This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.
    2 Both authors contributed equally.
    Affiliations
    Comprehensive Heart Failure Center and Dept. of Medicine I, University Hospital and University of Würzburg, Germany
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  • On behalf of the STAAB consortium
  • S. Frantz
    Affiliations
    Dept. of Medicine I, Div. of Cardiology, University Hospital Würzburg, Germany
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  • C. Maack
    Affiliations
    Comprehensive Heart Failure Center, University Hospital and University of Würzburg, Germany
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  • G. Ertl
    Affiliations
    University Hospital Würzburg, Germany
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  • M. Fassnacht
    Affiliations
    Dept. of Medicine I, Div. of Endocrinology, University Hospital Würzburg, Germany
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  • C. Wanner
    Affiliations
    Dept. of Medicine I, University Hospital Würzburg, Germany
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  • R. Leyh
    Affiliations
    Dept. of Cardiovascular Surgery, University Hospital Würzburg, Germany
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  • J. Volkmann
    Affiliations
    Dept. of Neurology, University Hospital Würzburg, Germany
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  • J. Deckert
    Affiliations
    Dept. of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital Würzburg, Germany
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  • H. Faller
    Affiliations
    Dept. of Medical Psychology, University of Würzburg, Germany
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  • R. Jahns
    Affiliations
    Interdisciplinary Bank of Biomaterials and Data Würzburg, University Hospital Würzburg, Germany
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  • Author Footnotes
    1 This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.
    2 Both authors contributed equally.
Published:October 30, 2018DOI:https://doi.org/10.1016/j.ijcard.2018.10.098

      Highlights

      • In a representative sample of the population of Wuerzburg, Germany, 12% of participants reported a migration background
      • Prevalence of hypertension, atherosclerotic disease, and diabetes was equal to individuals without migration background
      • By contrast, prevalence of obesity and metabolic syndrome was significantly higher in individuals with migration background
      • Individuals from Russia revealed the least favourable profile of cardiovascular risk factors

      Abstract

      Background

      About 20% of the German population have a migration background which might influence prevalence of preventable cardiovascular risk factors (CVRF).

      Methods

      We report data of the prospective Characteristics and Course of Heart Failure Stages A-B and Determinants of Progression (STAAB) cohort study investigating a representative sample of inhabitants of the City of Würzburg, Germany, aged 30 to 79 years. Individuals without migration background were defined as follows: German as native language, no other native language, and/or born in Germany. All other participants were defined as individuals with migration background.

      Results

      Of 2473 subjects (51% female, mean age 54 ± 12 years), 291 (12%) reported a migration background: n = 107 (37%) from a country within the EU, n = 117 (40%) from Russia, and n = 67 (23%) from other countries. Prevalence of hypertension, atherosclerotic disease, and diabetes mellitus was similar in individuals with and without migration background. By contrast, prevalence of obesity and metabolic syndrome was significantly higher in individuals with migration background, with the least favourable profile apparent in individuals from Russia (individuals without vs. with migration background: obesity 19 vs. 24%, p < 0.05; odds ratio: EU: 1.6, Russia: 2.2*, other countries: 0.6; metabolic syndrome 18 vs. 21%, p < 0.05; odds ratio: EU: 1.2, Russia: 1.7*, other countries: 1.5; *p < 0.05).

      Conclusion

      Individuals with migration background in Germany might exhibit a higher CVRF burden due to a higher prevalence of obesity and metabolic syndrome. Strategies for primary prevention of heart failure may benefit from deliberately considering the migration background.

      Keywords

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