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EAT: What role does the fat around the heart play?

Published:September 05, 2019DOI:https://doi.org/10.1016/j.ijcard.2019.08.023
      Obesity is on the rise, and with it, fatty heart tissue as well [
      • Packer M.
      Epicardial adipose tissue may mediate deleterious effects of obesity and inflammation on the myocardium.
      ]. Epicardial adipose tissue (EAT) and its relationship to cardiovascular disease have been attracting more attention over the last decade [
      • Wong C.X.
      • Ganesan A.N.
      • Selvanayagam J.B.
      Epicardial fat and atrial fibrillation: current evidence, potential mechanisms, clinical implications, and future directions.
      ]. EAT is a depot of fat surrounding the heart within the pericardial sack; located predominantly around coronary arteries and the atrioventricular groove as well as at distinct positions surrounding the atria [
      • Wong C.X.
      • Ganesan A.N.
      • Selvanayagam J.B.
      Epicardial fat and atrial fibrillation: current evidence, potential mechanisms, clinical implications, and future directions.
      ]. It is thus divided into peri-ventricular and peri-atrial EAT. The latter, or more specifically, left atrial adipose tissue (LAAT) is the focus of Lopez-Canoa and colleagues in the current issue of the International Journal of Cardiology.
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