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Research Article| Volume 329, P115-122, April 15, 2021

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Cost of inpatient heart failure care and 30-day readmissions in the United States

  • Author Footnotes
    1 Joint first author.
    ,
    Author Footnotes
    2 “This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation”.
    Chun Shing Kwok
    Footnotes
    1 Joint first author.
    2 “This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation”.
    Affiliations
    Keele Cardiovascular Research Group, Keele University, Stoke-on-Trent, UK

    Department of Cardiology, Royal Stoke University Hospital, Stoke-on-Trent, UK
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  • Dmitry Abramov
    Affiliations
    Keele Cardiovascular Research Group, Keele University, Stoke-on-Trent, UK

    Department of Cardiology, Royal Stoke University Hospital, Stoke-on-Trent, UK

    Department of Cardiology, Linda Loma University Health, Linda Loma, USA
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  • Purvi Parwani
    Affiliations
    Department of Cardiology, Royal Stoke University Hospital, Stoke-on-Trent, UK

    Department of Cardiology, Linda Loma University Health, Linda Loma, USA
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  • Raktim K. Ghosh
    Affiliations
    Department of Cardiology, Royal Stoke University Hospital, Stoke-on-Trent, UK

    Department of Cardiology, Case Western Reserve University, Heart and Vascular Institute, MetroHealth Medical Center, Cleveland, USA
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  • Michelle Kittleson
    Affiliations
    Department of Cardiology, Royal Stoke University Hospital, Stoke-on-Trent, UK

    Department of Cardiology, Cedars-Sinai Smidt Heart Institute, Los Angeles, CA, USA
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  • Fozia Z. Ahmad
    Affiliations
    Department of Cardiology, Royal Stoke University Hospital, Stoke-on-Trent, UK

    Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK
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  • Fakhr Al Ayoubi
    Affiliations
    Department of Cardiology, Royal Stoke University Hospital, Stoke-on-Trent, UK

    Department of Cardiac Sciences KFCC, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia
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  • Harriette G.C. Van Spall
    Affiliations
    Department of Cardiology, Royal Stoke University Hospital, Stoke-on-Trent, UK

    Department of Medicine, McMaster University, Hamilton, Canada

    Population Health Research Institute, Hamilton, Canada
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  • Mamas A. Mamas
    Correspondence
    Corresponding author at: Keele Cardiovascular Research Group, Keele University, Stoke-on-Trent, UK.
    Affiliations
    Keele Cardiovascular Research Group, Keele University, Stoke-on-Trent, UK

    Department of Cardiology, Royal Stoke University Hospital, Stoke-on-Trent, UK
    Search for articles by this author
  • Author Footnotes
    1 Joint first author.
    2 “This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation”.
Published:December 12, 2020DOI:https://doi.org/10.1016/j.ijcard.2020.12.020

      Highlights

      • Costs associated with heart failure hospitalizations in the United States vary greatly among hospitalized patients
      • Biggest comorbidity contributors to increased inpatient costs are pulmonary disorders, valvular heart disease, and bleeding
      • Invasive procedures are common in patients hospitalized with heart failure and significantly increase hospitalization costs
      • Heart Failure readmissions are frequent, and readmissions also significantly contribute to total hospitalization costs

      Abstract

      Background

      Heart failure hospitalizations are a major financial cost to healthcare systems. This study aimed to evaluate the costs associated with inpatient hospitalization.

      Methods

      Patients with a primary diagnosis of heart failure during a hospital admission between 2010 and 2014 in the U.S. Nationwide Readmission Database were included. The primary outcome was total cost defined by direct cost of index admission and first readmission within 30-days.

      Results

      A total of 2,645,336 patients with primary heart failure were included in the analysis. The mean ± SD total cost overall was $13,807 ± 24,145; with mean total costs of $15,618 ± 25,264 for patients with 30-day readmission and $11,845 ± 22,710 for patients without a readmission. The comorbidities strongly associated with increased cost were pulmonary circulatory disorder (OR 26.24 95% CI 20.06–34.33), valvular heart disease (OR 25.42 95% CI 20.65–31.28) and bleeding (OR 5.96 95% CI 5.47–6.50). Among hospitalized patients, 12.6% underwent an invasive diagnostic procedure or treatment. The mean cost for patients without invasive care was $10,995. This increased by $129,547, $119,769, $251,110 and $293,575 for receipt of circulatory support, intra-aortic balloon pump, LV assist device and heart transplant. The greatest mean additional cost annually was associated with receipt of coronary angiogram ($26,282 per person for a total of ($728.5 million) and mechanical ventilation ($54,529 per person for a total of $501.7 million).

      Conclusion

      In conclusion, the costs associated with inpatient heart failure care are significant, and the major contributors to inpatient costs are comorbidities, invasive procedures and readmissions.

      Keywords

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      Linked Article

      • How much is it to mend a broken heart? Results from the US Nationwide Readmission Database
        International Journal of CardiologyVol. 329
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          In the United States, the prevalence of heart failure (HF) is expected to rise from 2.4% in 2012 to 3.0% in 2030 [1]. This increase is related to the growing number of elderly individuals and the longer survival of many cardiac and noncardiac conditions possibly leading to HF development or decompensation. HF puts a significant strain on healthcare systems, and the overall cost of HF continues to rise [1]. In 2012, the total cost for HF was estimated to be $31 billion, and projections suggest that the total cost of HF will increase by 127% by 2030, to $70 billion, amounting to $244 for every US adult [1].
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