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Echocardiographic detection of heart valve disease in a community cohort of asymptomatic Australians > 65 years with cardiovascular risk factors

  • Author Footnotes
    1 Declarations of Interest: None.
    Nicholas D'Elia
    Correspondence
    Corresponding author.
    Footnotes
    1 Declarations of Interest: None.
    Affiliations
    Western Health Department of Cardiology, Baker Heart and Diabetes Institute, Melbourne, Australia
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  • Author Footnotes
    2 Declarations of interest: Dr. Gall has received funding from the Heart Foundation of Australia (GNT102061) and the National Health and Medical Research Council (GNT1182071).
    Seana Gall
    Footnotes
    2 Declarations of interest: Dr. Gall has received funding from the Heart Foundation of Australia (GNT102061) and the National Health and Medical Research Council (GNT1182071).
    Affiliations
    Menzies Institute for Medical Research, University of Tasmania; School of Medical Sciences, Monash University, Australia
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  • Author Footnotes
    1 Declarations of Interest: None.
    Elizabeth Potter
    Footnotes
    1 Declarations of Interest: None.
    Affiliations
    Baker Heart and Diabetes Institute, Australia
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  • Author Footnotes
    1 Declarations of Interest: None.
    Leah Wright
    Footnotes
    1 Declarations of Interest: None.
    Affiliations
    Baker Heart and Diabetes Institute, Australia
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  • Author Footnotes
    1 Declarations of Interest: None.
    Hilda Yang
    Footnotes
    1 Declarations of Interest: None.
    Affiliations
    Menzies Institute for Medical Research, University of Tasmania, Australia
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  • Thomas H. Marwick
    Affiliations
    Baker Heart and Diabetes Institute, Melbourne, Australia
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  • Author Footnotes
    1 Declarations of Interest: None.
    2 Declarations of interest: Dr. Gall has received funding from the Heart Foundation of Australia (GNT102061) and the National Health and Medical Research Council (GNT1182071).
Published:November 24, 2022DOI:https://doi.org/10.1016/j.ijcard.2022.11.045

      Highlights

      • Valvular Heart Disease is a very prevalent form of cardiac disease.
      • Aortic Stenosis and Mitral regurgitation are the most common forms of valvular heart disease.
      • The burden of valvular heart disease is likely to exponentially increase over the coming decades.

      Abstract

      Background

      Valvular heart disease is becoming an increasingly prevalent with population ageing. We sought to define the current prevalence of valvular heart disease in Australia.

      Methods

      The TasELF and VicELF studies prospectively recruited 962 asymptomatic participants ≥65 years, with at least one cardiovascular risk factor, from the Tasmanian and Victorian communities. People were excluded if they had a previous diagnosis of heart failure, or a life expectancy <1 year. All underwent baseline echocardiography. Those with moderate or severe valvular disease were identified. The current prevalence of clinically significant valve disease was applied to the Australian Bureau of Statistics population projections.

      Results

      Echocardiograms were interpretable in 943 participants (98%). Clinically significant valve disease was present in 5% of the population, and mitral regurgitation was the most common overall valvular lesion, present in 36% of the population. The projected numbers of people with clinically significant valvular disease is expected to increase significantly across all age groups by the year 2060.

      Conclusions

      Clinically significant yet asymptomatic valvular disease was prevalent in a large community cohort of participants with at least one risk factor. The total burden of valvular heart disease is expected to increase dramatically over the coming decades.

      Keywords

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