Traditionally, it was generally held that atrial fibrillation (AF) is a major cause
of ischemic cerebrovascular accident (ICVA) due to the blood flow stasis and thrombus
formation in a poorly contractile atrium and left atrial appendage during AF episodes.
Nevertheless, studies described a lack of a clear temporal association between AF
episodes and ICVA (
[1]
). Moreover, there is comparable incidence of ICVA between rate- and rhythm-control
strategies in AF. Therefore, in the absence of AF, an abnormal atrial substrate may
be the cause of embolism independent of AF (
[2]
). This fact may imply that AF is more likely a marker of ICVA in later stages of
abnormal atrial substrate. Hence, we should concentrate in finding ways of diagnosing
earlier stages of abnormal atrial substrate, instead of waiting for AF to appear.Abbreviations:
ECG left atrial abnormality. (Atrial Fibrillation)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: May 26, 2023
Accepted:
May 22,
2023
Received:
May 18,
2023
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2023 Elsevier B.V. All rights reserved.
